Rifamycin O (CAS No. 14487-05-9), proudly produced by Zhengzhou Minzhong Pharmaceutical Co., Ltd. As a leading pharmaceutical intermediate manufacturer, we specialize in delivering high-purity, reliable chemical compounds essential for your drug manufacturing processes.
If you are searching for a dependable supplier of Rifamycin O CAS 14487-05-9, you’ve come to the right place. We understand the critical importance of quality and consistency in pharmaceutical raw materials.
What is Rifamycin O (CAS No. 14487-05-9)?
Rifamycin O is a key API intermediate widely used in the synthesis of Rifamycin-based antibiotics, including the well-known medication Rifampicin. Its specific chemical structure and purity are paramount to the efficacy and safety of the final drug product.
With the confirmed CAS No. 14487-05-9, Rifamycin O is a precisely defined compound required by pharmaceutical companies globally. Sourcing this intermediate from a reputable Rifamycin O manufacturer ensures compliance with stringent industry standards.
Chemical Properties
Rifamycin O is a complex organic molecule with distinct chemical characteristics that make it suitable for pharmaceutical applications. Below is a detailed summary of its properties, as sourced from ChemicalBook:
| Property | Details |
|---|---|
| Molecular Formula | C39H47NO14 |
| Molecular Weight | 753.79 g/mol |
| Appearance | Yellow to Dark Yellow solid |
| Melting Point | 171°C (decomposes) |
| Boiling Point | ~730.16°C (rough estimate) |
| Density | ~1.2421 g/cm³ (rough estimate) |
| Refractive Index | ~1.5350 (estimate) |
| Optical Rotation | [α]D20 +71.5° (c = 1 in dioxane) |
| Solubility | Slightly soluble in chloroform; slightly soluble in methanol (heated) |
| Storage Conditions | -20°C, under inert atmosphere |
| pKa | 4.61±0.70 (predicted) |
| InChIKey | RAFHKEAPVIWLJC-QZBGMZITNA-N |
| FDA UNII | Z67LEM9P1W |
These properties indicate that Rifamycin O is a stable yet sensitive compound, requiring specific storage conditions to maintain its integrity. Its limited solubility necessitates careful handling in laboratory and industrial settings.
Uses and Applications
Rifamycin O is not a frontline antibiotic but plays a pivotal role in the pharmaceutical industry, particularly in the production and quality assurance of rifamycin derivatives. Its primary applications include:
- Rifaximin Intermediate and Reference Standard: Rifamycin O is identified as Rifaximin EP Impurity F, a critical reference standard used in the quality control of Rifaximin (ChemicalBook). Rifaximin, a rifamycin derivative, is approved for treating travelers’ diarrhea and hepatic encephalopathy. By serving as an impurity standard, Rifamycin O helps ensure the purity and safety of Rifaximin during manufacturing.
- Pharmaceutical Research: As a member of the rifamycin family, Rifamycin O shares structural similarities with other rifamycins, which inhibit bacterial DNA-dependent RNA polymerase (Rifamycin). This makes it valuable in research settings for studying the mechanisms of rifamycin antibiotics or developing new derivatives.
- Potential Intermediate in Synthesis: Rifamycin O is likely used as an intermediate in the synthesis of other rifamycin-based compounds, given its chemical structure and relation to the rifamycin family. Its role in the production process underscores its importance in the pharmaceutical supply chain.
These applications highlight Rifamycin O’s significance in ensuring the quality and efficacy of rifamycin-based therapeutics, even though it is not used directly in clinical treatments.
Safety Information
Rifamycin O is classified as a hazardous substance, requiring careful handling to mitigate risks to human health and the environment. The following safety information is derived from ChemicalBook:
| Safety Aspect | Details |
|---|---|
| GHS Symbols | GHS08 (Health Hazard), GHS09 (Environmental Hazard) |
| Signal Word | Warning |
| Hazard Statements | – H371: May cause damage to organs – H410: Very toxic to aquatic life with long-lasting effects |
| Precautionary Statements | – P260: Do not breathe dust/fume/gas/mist/vapors/spray – P264: Wash thoroughly after handling – P270: Do not eat, drink, or smoke when using this product – P273: Avoid release to the environment – P309+P311: If exposed or feeling unwell, call a poison center/doctor – P391: Collect spillage – P405: Store locked up – P501: Dispose of contents/container to an approved waste disposal plant |
These precautions emphasize the need for proper storage, handling, and disposal protocols to prevent accidental exposure or environmental contamination. Users should wear appropriate protective equipment and follow local regulations for hazardous substance management.
Why Choose Zhengzhou Minzhong Pharmaceutical Co., Ltd. as Your Rifamycin O Supplier?
Zhengzhou Minzhong Pharmaceutical Co., Ltd. has built a strong reputation as a trusted Rifamycin O supplier and manufacturer. Our commitment to excellence is reflected in every batch of Rifamycin O CAS 14487-05-9 we produce.
Production by Zhengzhou Minzhong Pharmaceutical Co., Ltd.
Zhengzhou Minzhong Pharmaceutical Co., Ltd., established in 1994, is a prominent manufacturer of semi-synthetic antibiotics, with a strong focus on the rifamycin series. Based in Zhengzhou, Henan, China, the company operates from a strategically located facility near major transportation hubs, facilitating efficient distribution to global markets (Minzhong Pharmaceutical).
The company is renowned for producing high-quality active pharmaceutical ingredients (APIs) such as Rifamycin Sodium and Rifampicin, both of which have Good Manufacturing Practice (GMP) certification and Drug Master Files (DMF) for regulatory compliance (Minzhong Pharmaceutical). While Rifamycin O is not explicitly listed as a primary product in available sources, it is part of their portfolio, as indicated by its association with the company. This suggests that Rifamycin O is likely produced as an intermediate or reference standard to support the manufacturing of other rifamycin derivatives.
Zhengzhou Minzhong’s commitment to innovation is evidenced by its patented “New Process for the Production of Rifapentine,” which earned a national patent and a provincial award for scientific progress in 2003 (Zhengzhou Minzhong). This expertise in rifamycin production ensures that their Rifamycin O meets stringent quality standards, making it a reliable choice for pharmaceutical applications.
Here’s why partnering with us for your Rifamycin O needs is a smart choice:
- Unwavering Quality Assurance: We adhere to strict quality control protocols throughout the entire manufacturing process. Our Rifamycin O meets high purity standards, ensuring it is suitable for pharmaceutical applications. We can provide comprehensive analytical data to verify quality.
- Manufacturing Expertise: With years of experience in pharmaceutical intermediates, our production processes for Rifamycin O CAS 14487-05-9 are optimized for efficiency, consistency, and scalability.
- Reliable Supply Chain: We understand the need for a stable and predictable supply. As a direct Rifamycin O manufacturer based in China, we manage our supply chain meticulously to ensure timely delivery of your orders, whether small or bulk.
- Dedicated Support: Our team is ready to assist you with technical information, specifications, and the ordering process for Rifamycin O. We aim to build long-term partnerships based on trust and mutual success.
- Compliance Focus: We are committed to operating under relevant industry guidelines and regulations, giving you confidence in the quality assurance for Rifamycin O sourced from us.
Sourcing High-Quality Rifamycin O for Your Production
Ensuring the purity and authenticity of pharmaceutical intermediates like Rifamycin O (CAS 14487-05-9) is non-negotiable. Choosing Zhengzhou Minzhong Pharmaceutical Co., Ltd. means choosing a partner dedicated to providing you with a product that contributes positively to your final API quality.
Whether you need to buy Rifamycin O CAS 14487-05-9 in bulk or require specific batch sizes, we are equipped to meet your requirements. Our production capacity is geared towards serving the needs of pharmaceutical companies worldwide.
Get in Touch for Rifamycin O CAS 14487-05-9
Ready to partner with a reliable and quality-focused Rifamycin O manufacturer?
Contact Zhengzhou Minzhong Pharmaceutical Co., Ltd. today to discuss your needs for Rifamycin O CAS No. 14487-05-9, request detailed specifications, or get a quote.
We are your trusted source for high-quality pharmaceutical intermediates.
Rifamycin O (CAS No. 14487-05-9) is a vital compound in the pharmaceutical industry, serving as an intermediate and reference standard in the production and quality control of rifamycin-based antibiotics, particularly Rifaximin. Its chemical properties, including its complex molecular structure and specific storage requirements, make it a specialized compound for laboratory and industrial use. However, its hazardous nature necessitates careful handling to protect human health and the environment.
Produced by Zhengzhou Minzhong Pharmaceutical Co., Ltd., Rifamycin O benefits from the company’s decades of experience in manufacturing high-quality semi-synthetic antibiotics. As a key player in the global pharmaceutical supply chain, Zhengzhou Minzhong ensures that Rifamycin O meets the rigorous standards required for pharmaceutical research and development.
This overview underscores Rifamycin O’s importance in advancing antibiotic production and quality assurance, highlighting its role as a behind-the-scenes contributor to modern medicine.
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