Rifampicin CAS No. 13292-46-1 by Zhengzhou Minzhong Pharmaceutical Co Ltd

Rifampicin is a potent antibiotic widely used in the treatment of various bacterial infections, including tuberculosis (TB) and leprosy. It works by inhibiting the synthesis of bacterial RNA, effectively stopping the growth and spread of bacteria. As a critical medication in the fight against TB, Rifampicin is an essential drug listed by the World Health Organization (WHO).

Product name:
Rifampicin (Rifampin)
CAS No.
13292-46-1
Chemical name:
3-(4-Methyl-1-piperazinyl imino) rifamycin SV
Molecular formula:
C43 H58N4O12
Molecular weight:
822.95
Applications:
Antibiotics for the treatment of tuberculosis.
Appearance:
A Reddish Brown to Brownish Red Crystalline powder.
Specification:
BP/USP/EP.
Bulk Density:
0.5g/ml; 0.7g/ml
Standard Packaging:
25kgs/drum

Zhengzhou Minzhong Pharmaceutical Co Ltd: Leading the Way in Rifampicin Production

Zhengzhou Minzhong Pharmaceutical Co Ltd is a renowned manufacturer of Rifampicin, committed to providing high-quality pharmaceutical products. Located in Zhengzhou, China, Minzhong Pharmaceutical has established itself as a reliable supplier in the global market, known for its stringent quality control measures and advanced manufacturing processes.

Quality and Compliance

At Zhengzhou Minzhong Pharmaceutical Co Ltd, quality is paramount. The company adheres to Good Manufacturing Practices (GMP) and international standards, ensuring that each batch of Rifampicin meets the highest quality criteria. Their state-of-the-art facilities are equipped with modern technology to produce Rifampicin that is both effective and safe for use.

Global Reach and Customer Satisfaction

With a strong presence in the international market, Zhengzhou Minzhong Pharmaceutical Co Ltd has built a robust distribution network, ensuring timely delivery of Rifampicin to various parts of the world. The company prides itself on its excellent customer service and support, catering to the needs of healthcare providers and patients alike.

Innovation and Research

Zhengzhou Minzhong Pharmaceutical Co Ltd invests heavily in research and development to continuously improve their products and processes. By staying at the forefront of pharmaceutical innovation, the company ensures that its Rifampicin remains effective against resistant strains of bacteria, contributing to global health and well-being.

Zhengzhou Minzhong Pharmaceutical Co Ltd is a trusted name in the production of Rifampicin, providing high-quality and effective solutions for bacterial infections. With their commitment to quality, compliance, and innovation, Minzhong Pharmaceutical is a key player in the global pharmaceutical industry.

Chemical name: 3-(4-methyl-1-piperazinyl-iminomethyl)-rifamycin SV, molecular formula C43H58N4O12, molecular weight 822.97. This product is bright red or dark red crystalline powder, odorless and tasteless. Rifampicin is a highly effective broad-spectrum antibiotic. It is mainly used in combination with other anti-nuclear drugs for severe patients with various nuclear diseases. It can also be used as a substitute for isoniazid and streptomycin-resistant strains. It is also effective against infections caused by drug-resistant Staphylococcus aureus, pneumococcus and other bacteria. Especially, it has a good effect in treating biliary tract infections and can also be used to treat leprosy. The dosage forms include tablets, capsules, compound preparations and rifampicin for injection. The rifampicin of our company is bright red in color and has good fluidity, which is suitable for capsules and tablets.

Rifampicin (CAS 13292-46-1) Interactive | Zhengzhou Minzhong Pharmaceutical
CAS NO. 13292-46-1

Rifampicin API

A high-quality, GMP-certified Active Pharmaceutical Ingredient for treating tuberculosis and other severe bacterial infections. Produced by Zhengzhou Minzhong Pharmaceutical Co Ltd.

Chemical & Physical Properties

Key data points for Rifampicin API, providing essential information for formulation and handling.

Molecular Formula

C₄₃H₅₈N₄O₁₂

Molecular Weight

822.94 g/mol

Appearance

Red-Brown Powder

Melting Point

183-188°C (dec.)

Solubility

Soluble in chloroform & methanol; practically insoluble in water.

Stability

Hygroscopic and light-sensitive. Requires controlled storage.

Therapeutic Applications

Rifampicin is a cornerstone antibiotic for several critical treatments. Select an application below to see more details.

Cornerstone of TB Treatment

Rifampicin is an essential first-line drug in multi-drug combination therapy for *Mycobacterium tuberculosis*. Its potent bactericidal action rapidly reduces the bacterial load, making it critical for treating both drug-sensitive and some forms of drug-resistant TB.

Antimicrobial Activity Spectrum

Rifampicin exhibits potent activity against a range of microorganisms, with particularly high efficacy against mycobacteria.

A History of Quality & Trust

Since 1994, Zhengzhou Minzhong Pharmaceutical has been committed to API manufacturing excellence, backed by global certifications.

2020: GMP Compliance Renewal

Renewed production license and obtained updated GMP compliance documents.

2008: European COS Authentication

Rifampicin passed the Certificate of Suitability (COS), affirming compliance with European Pharmacopoeia standards.

2004: GMP Certification

Our Rifampicin API acquired its official GMP (Good Manufacturing Practice) certificate.

1994: Company Established

Zhengzhou Minzhong Pharmaceutical Co Ltd was founded.

Safety, Handling & Storage

Rifampicin is a potent API and must be handled according to strict safety protocols. Always consult the full Safety Data Sheet (SDS).

Drug Interactions

Potent inducer of liver enzymes, affecting metabolism of other drugs.

Adverse Effects

Can include hepatotoxicity and hypersensitivity. Requires monitoring.

Body Fluid Discoloration

A common, non-harmful effect is red-orange discoloration of urine, tears, etc.

Storage Conditions

Store at 2-8°C. Protect from light and moisture as it is hygroscopic.

Partner with a Trusted API Manufacturer

For a reliable, high-quality supply of Rifampicin API, trust the certified expertise of Zhengzhou Minzhong Pharmaceutical Co Ltd.

Contact Us

© Zhengzhou Minzhong Pharmaceutical Co Ltd. All rights reserved.

Zhengzhou Minzhong Pharmaceutical Co Ltd | Leading Rifamycin API Manufacturer Since 1994

Zhengzhou Minzhong Pharmaceutical Co Ltd | Leading Rifamycin API Manufacturer Since 1994 | GMP & COS Certified
GMP & COS Certified Manufacturer

China's Trusted Rifamycin API Manufacturer Since 1994

Zhengzhou Minzhong Pharmaceutical Co., Ltd. is a professional enterprise specializing in the research, production, and global distribution of semi-synthetic antibiotic APIs — serving pharmaceutical companies across 30+ countries with GMP-certified Rifamycin derivatives.

30+
Years Experience
30+
Export Countries
9+
API Products
Zhengzhou Minzhong Pharmaceutical Co Ltd manufacturing facility and production line
Established
Since 1994
Certification
GMP · COS · DMF
🏭
5,000+ M² Facility
GMP Certified
🇪🇺
European COS Approved
📋
DMF Holder
🌍
Exported to 30+ Countries
Zhengzhou Minzhong Pharmaceutical production facility and stainless steel equipment
30+
Years of Excellence

A Pioneer in Rifamycin Derivative Manufacturing

Zhengzhou Minzhong Pharmaceutical Co., Ltd., established in 1994, is a professional enterprise dedicated to the research, production, and global sales of semi-synthetic antibiotic raw materials and pharmaceutical products. Strategically located on the Zhengbian Industrial Belt in Henan Province, the company enjoys excellent connectivity via National Highway 107, the Beijing-Hong Kong-Macau Expressway, Longhai Railway, and is just 11 kilometers from Zhengzhou Xinzheng International Airport.

The company independently developed the "New Process for the Production of Rifapentine", which earned a national patent and the second prize for major scientific and technological progress in Henan Province in 2003. In 2005, the products were jointly recognized as "National Key New Products" by the Ministry of Science and Technology, the Ministry of Commerce, and other national agencies.

Minzhong Pharma maintains long-term technical cooperation with the Sichuan Antibiotics Research Institute, China Medical Group, and the Pharmaceutical Research Institute of Zhengzhou University, ensuring strong R&D capabilities and continuous innovation.

🔬
Advanced R&DPatented production processes
🏅
National RecognitionHigh-tech enterprise award
🤝
Research PartnershipsTop Chinese institutions
🌿
SustainabilityEco-friendly manufacturing

Premium Rifamycin Derivative APIs & Intermediates

Zhengzhou Minzhong Pharmaceutical manufactures a comprehensive range of active pharmaceutical ingredients and intermediates, all produced under strict GMP conditions and meeting international pharmacopoeia standards.

Active Pharmaceutical Ingredients (APIs)

💊

Rifampicin

CAS No. 13292-46-1

A first-line anti-tuberculosis antibiotic API widely used in the treatment of TB and other mycobacterial infections. Produced under GMP with European COS compliance.

API
Learn More
💊

Rifamycin Sodium

CAS No. 14897-39-3

A semi-synthetic antibiotic used as a key raw material in the production of various Rifamycin derivative drugs. GMP certified with DMF documentation available.

API
Learn More
💊

Rifabutin

CAS No. 72559-06-9

An ansamycin antibiotic used for the prevention and treatment of Mycobacterium avium complex (MAC) disease, particularly in immunocompromised patients.

API
Learn More
💊

Rifapentine

CAS No. 61379-65-5

A long-acting Rifamycin derivative for tuberculosis treatment. Minzhong's patented production process earned national recognition and European COS certification.

API
Learn More
💊

Rifaximin

CAS No. 80621-81-4

A non-absorbable antibiotic used for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy. High-purity pharmaceutical grade.

API
Learn More
💊

Piroxicam

CAS No. 36322-90-4

A non-steroidal anti-inflammatory drug (NSAID) API used in the treatment of rheumatoid arthritis, osteoarthritis, and other inflammatory conditions.

API

Pharmaceutical Intermediates

⚗️

Rifamycin S

CAS No. 13553-79-2

A critical intermediate in the synthesis of various Rifamycin derivative antibiotics. Manufactured with high purity and consistent quality for downstream API production.

Intermediate
Learn More
⚗️

Rifamycin O

CAS No. 14487-05-9

An important pharmaceutical intermediate used in the production pathway of Rifamycin-class antibiotics. Available in bulk quantities for industrial applications.

Intermediate
Learn More
⚗️

Sodium Rifamycin S

CAS No. 133956-65-7

The sodium salt form of Rifamycin S, offering enhanced solubility for pharmaceutical manufacturing processes. Produced under strict quality control protocols.

Intermediate
Learn More

Your Reliable Rifamycin API Partner

With over three decades of specialized expertise, Zhengzhou Minzhong Pharmaceutical delivers unmatched quality, regulatory compliance, and global supply reliability.

🏆

30+ Years Expertise

Dedicated exclusively to Rifamycin derivatives since 1994, with patented production processes and deep domain knowledge.

🔬

Advanced R&D

State-of-the-art Hewlett-Packard analytical equipment, partnerships with leading Chinese research institutes, and continuous innovation.

Triple Certified

GMP certified, European COS approved, and DMF holder — meeting the most stringent international pharmaceutical standards.

🌍

Global Reach

Products registered and exported to India, Russia, Brazil, Mexico, Europe, Southeast Asia, and 30+ countries worldwide.

International Certifications & Registrations

Zhengzhou Minzhong Pharmaceutical maintains the highest quality standards with internationally recognized certifications, ensuring every API meets rigorous safety and efficacy requirements.

Zhengzhou Minzhong Pharmaceutical GMP Certificate - Good Manufacturing Practice certification for API production

GMP Certification

Good Manufacturing Practice certification ensuring products are consistently produced and controlled according to the highest quality standards. First certified in 2004, with new-version GMP achieved in 2015.

Zhengzhou Minzhong Pharmaceutical European COS Certificate - Certificate of Suitability to European Pharmacopoeia

European COS Certification

Certificate of Suitability to the European Pharmacopoeia (CEP/COS), confirming compliance with European quality standards. Rifapentine COS certified since December 2008.

Zhengzhou Minzhong Pharmaceutical DMF and additional COS certification documentation

DMF & Global Registrations

Drug Master File holder providing transparent manufacturing data for regulatory support. Products registered in India, Ukraine, Russia, Brazil, Mexico, and across Southeast Asia and Europe.

State-of-the-Art GMP Production Facility

Zhengzhou Minzhong Pharmaceutical operates a modern manufacturing facility spanning over 5,000 square meters in Zhengzhou, China. The facility features modern stainless steel pharmaceutical equipment, highly automated GMP-standard workshops, and advanced Hewlett-Packard microelectronic inspection, analysis, and detection equipment.

Dedicated areas for raw material storage, production, quality control, and packaging ensure complete process integrity. The company also operates a second production base — Kaifeng Minzhong Pharmaceutical Co., Ltd. — which commenced production in 2025, further expanding manufacturing capacity.

5,000+
Sq. Meters
2
Production Bases
GMP
Standard
Zhengzhou Minzhong Pharmaceutical GMP-certified production equipment and automated manufacturing line

Three Decades of Pharmaceutical Excellence

From our founding in 1994 to becoming a globally recognized Rifamycin API manufacturer, every milestone reflects our commitment to quality and innovation.

1994

Company Founded

Zhengzhou Minzhong Pharmaceutical Co., Ltd. established as a professional Rifamycin derivatives manufacturer.

2003

National Patent & Award

"New Process for the Production of Rifapentine" won national patent and second prize for major scientific and technological progress in Henan Province.

2004

GMP Certification

Rifamycin Sodium and Rifampicin passed GMP certification from the State Drug and Food Administration.

2005

National Key New Products

Products jointly recognized as "National Key New Products" by four national ministries and administrations.

2006

High-Tech Enterprise

Received "High-tech Product" certificate and included in "China High-tech Product Export Catalog." Awarded "High-tech Enterprise" status.

2008

European COS Certification

Rifapentine passed the European Certificate of Suitability (COS) certification, opening doors to European pharmaceutical markets.

2015

New GMP Standard

Successfully passed the new-version GMP certification, demonstrating continued commitment to the highest manufacturing standards.

2020

License Renewal & GMP Compliance

Renewal of production license and obtaining updated GMP compliance documents.

2024

WC Certificate

Rifamycin Sodium obtained WC certificate, further strengthening global market access.

2025

Kaifeng Production Base

Kaifeng Minzhong Pharmaceutical Co., Ltd. commenced production, expanding the company's manufacturing capacity.

Common Questions About Minzhong Pharmaceutical

Zhengzhou Minzhong Pharmaceutical specializes in Rifamycin derivative APIs including Rifampicin (CAS 13292-46-1), Rifamycin Sodium (CAS 14897-39-3), Rifabutin (CAS 72559-06-9), Rifaximin (CAS 80621-81-4), Rifapentine (CAS 61379-65-5), and Piroxicam (CAS 36322-90-4). The company also produces pharmaceutical intermediates such as Rifamycin S, Rifamycin O, and Sodium Rifamycin S.
Yes. Zhengzhou Minzhong Pharmaceutical first obtained GMP certification in 2004, passed recertification in 2009 (Certificate No.: Yu K0098), and achieved new-version GMP certification in 2015. The company also holds European COS certification for Rifapentine (since 2008) and is a DMF holder, ensuring full regulatory compliance for global markets.
Minzhong Pharmaceutical exports its APIs to over 30 countries and regions including India, Ukraine, Russia, Brazil, Mexico, and numerous markets across Southeast Asia and Europe. Products are registered in multiple countries to ensure smooth regulatory compliance for international customers.
Minzhong Pharmaceutical stands out with over 30 years of exclusive focus on Rifamycin derivatives, a patented production process for Rifapentine, triple certification (GMP, COS, DMF), long-term partnerships with leading Chinese research institutions, and a 5,000+ square meter state-of-the-art manufacturing facility with two production bases. The company has been recognized as a national "High-tech Enterprise" and "double-excellent" foreign investment enterprise.
Yes. Zhengzhou Minzhong Pharmaceutical offers bespoke synthesis solutions ranging from small-scale research quantities to large-scale commercial production. The company's advanced synthesis capabilities, process optimization expertise, and state-of-the-art analytical laboratories enable them to meet unique client requirements across the Rifamycin product family.
You can request a quotation by contacting Minzhong Pharmaceutical directly via email at info@minzhongpharma.com, by phone at +86-371-65797114, or through WhatsApp/WeChat at +86 173 3535 0289. You can also fill out the inquiry form on this page or visit the official website at minzhongpharma.com/contact/ for additional contact options.

Ready to Source Premium Rifamycin APIs?

Partner with Zhengzhou Minzhong Pharmaceutical — 30+ years of trusted quality, GMP & COS certified, serving pharmaceutical companies in 30+ countries worldwide.

Contact Zhengzhou Minzhong Pharmaceutical

Whether you need product inquiries, sales quotations, partnership discussions, or technical support — our team is ready to assist you.

📍

Head Office

Intersection of Sigangliandong Ave. & Zhengshang Rd., Economic Development Zone, Zhengzhou, China 451472

📞

Phone & Fax

Tel: +86-371-65797114 / 65797115

Fax: +86-371-65797120

💬

WhatsApp / WeChat

+86 173 3535 0289

🏭

Production Base 1

Development Area of Xiezhuang, Zhongmou County, Zhengzhou, China

🏭

Production Base 2 (Kaifeng)

Kaifeng Fine Chemical Development Zone, Wangtun Township, Yuwangtai District, Kaifeng, China

Send Us an Inquiry

My Instagram